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TīmeklisElevated synovial levels of IL-6 have been observed in patients with active RA and PsA.156 157 In RA, IL-6 is believed to upregulate the expression of endothelial adhesion molecules during osteoclast maturation and bone erosion.157 In PsA, IL-6 is produced by activated Th17 cells, inducing expression of IL-12 and IL-23, which … TīmeklisMagnetic resonance (MR) imaging provides excellent depiction of soft-tissue abnormalities of the joints affected by RA, which allows detection of early changes. Nineteen joints of 17 patients with RA were studied with surface-coil MR imaging. Measurable abnormalities demonstrated by MR imaging but not clearly seen on plain … momio clothes
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