Pithed rats
WebbAngiotensin-(1–7) is a novel peptide of the reninangiotensin system that counteracts the pressor and proliferative responses to angiotensin II. We now report that cultured bovine aortic endothelial cells contain a saturable, high-affinity [ 125 WebbIt is concluded that in the pithed rat angiotensin II produced an increase in myocardial contractile force which is not mediated by beta- or alpha-adrenoceptors. The inotropic effect appears to be mediated by angiotensin receptors, of the AT1-subtype.
Pithed rats
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WebbDavid Centurión Pacheco was born in Campeche, Camp. Mexico on 1st. October 1971. He obtained the degree of Pharmacist in 1995. Subsequently, he enrolled as a postgraduate student at the Department of Pharmacology of Cinvestav (Center for Research and Advanced Studies, Mexico City). He obtained the M.Sc. degree in December 1997 and … WebbThe pithed rat is a well-established experimental model for studying cardiovascular function [4,51] and has been further optimised for investigating the pharmacological profile of the receptors that modulate, at the peripheral level, the activity of the sympathetic and …
WebbAbstract. 1 The selectivity and specificity of RX 781094 [2- (2- (1,4 benzodioxanyl))2-imidazoline HCl] for alpha-adrenoceptors have been examined in peripheral tissues. 2 In isolated tissue experiments RX 781094 was a competitive antagonist at prejunctional … WebbProtocol for studying the effect of RWJ-356125 on H3 Autoreceptors in pithed rats. McQueen, Daniel (Principal Investigator) Deanery of Biomedical Sciences; Overview; Project Details Status: Finished: Effective start/end date: 1/02/02 → 1/03/02: Funding ...
WebbRecent clinical studies demonstrated that transient postprandial hyperglycemia and hyperinsulinemia may contribute to the development of hypertension. Therefore, we investigated influence of acute hyperglycemia and/or hyperinsulinemia induced by glucose or insulin infusion on neuronal and humoral control of vascular tone in rats. Euglycemic … WebbAbstract. The influence of the prejunctional beta-adrenoceptor-mediated control mechanism of noradrenaline release on the cardiovascular response to preganglionic nerve stimulation (PNS) and the role of adrenaline as endogenous activator of this …
Webb22 mars 2024 · The pithed rat is a well-established experimental model for studying cardiovascular function [ 4, 51] and has been further optimised for investigating the pharmacological profile of the receptors that modulate, at the peripheral level, the …
WebbMyocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading causes of morbidity and mortality worldwide. Serotonin (5-HT) release during myocardial ischemia plays an important role in the progression of myocardial cellular injury. This study was conducted to investigate the possible cardioprotective effect of flibanserin (FLP) … laney\u0027s computers altavistaWebb9 nov. 2024 · Number of pithed rats used in the two main sets (set 1: diabetic rats; set 2: normoglycaemic rats) as well as their divisions into further treatments (n = 5 each, with no exception). hemolysis post tavrWebbIn diabetic pithed rats, administration of the selective 5-HT1D receptor antagonist BRL-15572 (2 mg/kg) does not modify the decreased HR induced by vagal electrical stimulation. The effects of L-694,247 (50 μg/kg), a selective agonist for non-rodent 5-HT1B and 5-HT1D receptors, on the vagally induced bradycardia are not apparent after pretreatment with … laney\\u0027s difficulty chart obby