Web26 jul. 2024 · Our findings show that direct chemical reprogramming can generate hepatocyte-like cells with high-quality physiological properties, providing a paradigm for … Web31 mei 2024 · We successfully converted hepatocytes isolated from adult mice into expandable and stable leucine-rich repeat-containing G-protein-coupled receptor 5 …
Small molecule-mediated reprogramming of human hepatocytes …
Web25 jun. 2014 · Our data provide insight into the process by which direct hepatic reprogramming occurs in human cells. More importantly, by demonstrating that it is … Web4 dec. 2024 · SIGNIFICANCE We evaluated the clinical relevance of hepatocyte-driven ICC model and revealed critical but distinct roles of YAP1 and SOX9 in AKT-NICD-driven … star trek the motion picture cast photo
Nuclear factor programming improves stem-cell-derived …
Web3 jul. 2024 · In the first step, we used a combination of 5 hepatic transcription factors to reprogram fibroblasts into proliferative hepatic progenitor cells, which could then be … Web3 aug. 2024 · The hepatocyte reprogramming was under tight cooperative control of a network of fibrosis-activated transcription factors, as exemplified by the transcription … Web14 mrt. 2024 · The liver’s remarkable regenerative capacity depends on the plasticity of hepatocytes and cholangiocytes. Although the contribution of each cell type to liver repair … star trek the motion picture ebert