WebAug 3, 2024 · The concentration profile of a reaction shown in Figure 1. The reaction used 0.3 equiv. of DBU to achieve greater conversion during the experiment. In the shown experiment, the ring-opening of 1 to 3 was … Web14 DBU Derived Ionic Liquids and Their Application in Organic Synthetic Reactions Xinzhi Chen 1 and Anguo Ying 2 1Department of Chemical and Biochemical En gineering, Zhejiang University, Hangzhou, 2School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou, P.R. China 1. Introduction With the continuing depletion of …

DBU-catalyzed [3 + 2] cycloaddition and Michael addition …

WebDec 5, 2024 · DBU catalyzed ROP of CL, VL and TMC. a a Reaction conditions: 90 °C in bulk with the initial ratio of DBU to initiator was 1:1, BnOH was used as the initiator. b Initial molar ratio of monomer to initiator. c Determined by 1 H NMR. d Calculated from ( [M] 0 / [I] 0 ) × Conv.× (MW of CL)+ (MW of initiator). e Determined by SEC. f Without DBU. g WebOct 21, 2024 · DBU (1,8-diazabicyclo [5.4.0]undec-7-ene) is a strong tertiary amine base (pH 12.8) with a double heterocyclic structure, which has been widely used in organic synthesis. The two N atoms in the molecule have sp2, sp3 hybrid state, respectively. Both N 1 ( sp3) and N 8 ( sp2) have a pair of lone electrons exposed in different directions … jim marchant personal life

氮杂环卡宾催化的亲核取代反应

WebAug 3, 2024 · The protocol comprises of an amidine catalyzed relay ring-opening and fragmentation of 3,4-dihydropyranones. The reaction proceeds under mild conditions, has a broad substrate scope and the products can be isolated in good to excellent yields. WebSep 30, 2012 · In addition to gold salts, other transition metal catalysts have also been reported to exhibit better catalytic activity. For instance, Yang and co-workers revealed the Ni(acac) 2 and Yb(OTf) 3 combined catalyst system for the cyclization of alkynyl β-ketoesters 1 to give exo-methylenecycloalkanes 9a–i (Scheme 5). 18 It should be … WebJan 1, 2024 · In conclusion, we have reported a DBU-catalyzed deamination reaction of propargylamines and water that lead to produce valuable chalcones under metal-free conditions. Preliminary mechanistic studies indicated that the DBU promoted the isomerization of propargylamine to allenylamine through 1,3-proton transfer. jim marchant ballotpedia