Cisplatin komplex
WebA detailed analysis of the cisplatin-resistant phenotype indicated that it was associated with reduced cisplatin accumulation, reduced interstrand cross-link (ICL) formation and DNA … WebCisplatin is also sometimes used to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue, palate, throat, tonsils, and sinuses), lung cancer, cancer of the cervix and esophagus, brain tumors, malignant pleural mesothlioma (cancer in the lining of the chest or abdomen), and neuroblastoma (a cancer that begins in nerve cells and …
Cisplatin komplex
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Webcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths injectable... WebDec 16, 2024 · IntroductionCisplatin, a chemotherapeutic drug, is widely used for the treatment of various malignant tumors with good effects. However, cisplatin-induced nephrotoxicity is a major dose-limiting factor and a significant adverse event. Mannitol is used to reduce cisplatin-induced nephrotoxicity, which is controversial. This study …
WebSep 15, 2024 · DESCRIPTION. Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL … WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important. Ubiquitin-specific protease (USP14) is involved in various pathological conditions ...
WebThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon-like peptide-1 receptor agonist (GLP-1R), w … WebCisplatin for injection has been administered at 75 mg/m. 2 . to 100 mg/m. intravenously per cycle once every 3 to 4 weeks on Day 1. Other doses and combination regimens have been used. 2.4 Advanced Bladder Cancer . Cisplatin for injection has been administered at 50 mg/m. 2 . to 70 mg/m. intravenously per cycle once every 3 to 4 weeks.
WebJul 13, 2012 · Cisplatin and IR combination therapy display schedule and dose-dependent synergy, the mechanism of which is not completely understood. In a series of in vitro and …
WebApr 9, 2024 · Die Platin(II)-Komplexe Cisplatin, Oxaliplatin und Carboplatin gehören unter anderem zu den am häufigsten eingesetzten Krebsmedikamenten. ... hat sein Team erstmals Platin(IV)-Komplex-Prodrugs mit Sonosensibilisatoren kombiniert, die mit Ultraschallbestrahlung selektiv aktiviert werden können. Nach der Bestrahlung mit … china eatery oob maineWebDec 8, 2024 · Here, we elucidate the effect of cisplatin on the MRN (MRE11-RAD50-NBS1) DNA damage sensor complex. We found that the tumor suppressor FBXW7 is a key factor in controlling the turnover of the MRN... china eatery abingtonCisplatin (cis-Diammindichloridoplatin; DDP) ist ein Arzneistoff (Zytostatikum zur Hemmung des Zellwachstums bzw. der Zellteilung) und enthält ein komplexgebundenes Platinatom. Die Wirkung beruht auf einer Hemmung der DNA-Replikation durch Querverknüpfungen zweier benachbarter … See more Cisplatin wurde zuerst 1844 von Michele Peyrone synthetisiert, damals bekannt als Peyrones Chlorid. Es spielte eine Rolle bei der Entwicklung der Komplexchemie durch Alfred Werner. Die Entdeckung der zytostatischen … See more Wirkungsmechanismus Cisplatin wirkt ähnlich wie bifunktionelle Alkylantien durch Querverknüpfungen von DNA-Strängen. Der stark elektrophile Aqua-Cisplatin … See more • Markus Galanski, Bernhard K. Keppler: Tumorhemmende Metallverbindungen. In: Pharmazie in unserer Zeit 35(2), S. 118–122 (2006), • Ingo Ott, Ronald Gust: Medizinische … See more Cisplatin stellt einen planaren Komplex dar, der am zentralen Platinatom zwei cis-ständige Chloridliganden und zwei Amminliganden gebunden hat (zur genaueren Erläuterung der Nomenklatur von Komplexverbindungen siehe Komplexchemie). … See more Monopräparate Cis-GRY (D), Platiblastin (CH), Platinol (CH), zahlreiche Generika (D, A, CH). See more grafton transportationWebOral squamous cell carcinoma (SCC) is one of the most predominant tumors worldwide and the present treatment policies are not enough to provide a specific solution. We aimed to assess the cytotoxic effect of Cu(II)–Mn(II) Schiff base tetradentate complex alone or in combination with cisplatin against squamous cell carcinoma cell line (SCCs) in vitro. … china eatery old orchard beach menuWebYou usually have cisplatin as cycles of treatment. Each cycle varies depending on what type of cancer you have. You might have cisplatin: every 3 or 4 weeks. once a week. every day over a 5 day period, every 3 to 4 weeks. You might have cisplatin on its own or in combination with other cancer treatments such as different chemotherapy drugs or ... china eatery oob menuWebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body. This medicine is to be given only by or under the direct supervision of a doctor. grafton treatment centerWebOct 11, 2013 · Cisplatin is one of the most potent anticancer agents available today and is widely used in the treatment of many malignancies, including testicular, ovarian, bladder, … grafton truck and trailer repairs